ATIC

Across TCGA patient cohorts, ATIC RNA expression is significantly associated with the protein abundance of many other proteins, with 15,055 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATIC-associated proteins across cancer lineages are DTYMK, UTP18, and RAE1. Each is linked with ATIC in more than 6 cancer types. Because this analysis shows association rather than direction, both ATIC-to-partner and partner-to-ATIC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATIC versus DTYMK in UCEC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATIC→partner) and Y-score (partner→ATIC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DTYMK →	+0.290	+0.457	<.001	.001	3	7
LSCC	UTP18 →	+0.329	+0.533	<.001	<.001	3	6
COAD	RAE1 →	+0.200	+0.296	<.001	<.001	3	6
UCEC	RBM39 →	+0.229	+0.479	<.001	<.001	3	6
UCEC	WDR12 →	+0.416	+0.627	<.001	<.001	3	6
PDAC	XRCC6_T455 →	+0.629	+0.449	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,055 associations by consensus.

ATIC vs DTYMK — UCEC

Explore this scatter interactively →