ATG9B

Across TCGA patient cohorts, ATG9B mutation is significantly associated with the RNA expression of many other genes, with 1,932 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATG9B-associated genes across cancer lineages are RN7SKP15, TIMM9P1, and EGFLAM-AS1. Each is linked with ATG9B in more than 2 cancer types. Because this analysis shows association rather than direction, both ATG9B-to-partner and partner-to-ATG9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP15 grouped by ATG9B-low versus ATG9B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG9B→partner) and Y-score (partner→ATG9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP15 →	+0.254	+4.595	.002	.004	3	3
CESC	TIMM9P1 →	+0.176	+4.320	.004	.007	3	2
CESC	EGFLAM-AS1 →	+0.228	+4.409	<.001	.006	3	2
UCEC	VTI1A →	+0.341	+2.191	.005	.002	3	2
SKCM	SUPV3L1 →	+0.496	+2.604	.002	.006	3	2
UCEC	PAXIP1 →	+0.473	+3.671	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,932 associations by consensus.

RN7SKP15 by ATG9B expression — COAD

Explore this box plot interactively →