ATG9B

Across TCGA cell cohorts, ATG9B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,904 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ATG9B-associated GO terms across cancer lineages are Positive regulation of autophagy, Transcription pausing by RNA polymerase II, and Regulation of myoblast fusion. Each is linked with ATG9B in more than 10 cancer types. Because this analysis shows association rather than direction, both ATG9B-to-partner and partner-to-ATG9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of autophagy grouped by ATG9B-low versus ATG9B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG9B→partner) and Y-score (partner→ATG9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of autophagy →	+0.049	+1.301	<.001	<.001	3	10
KIDNEY	Transcription pausing by RNA polymerase II →	+0.108	+1.132	<.001	.005	3	10
LUNG_SCLC	Regulation of myoblast fusion →	+0.109	+2.059	<.001	<.001	3	10
LARGE_INTESTINE	Cilium or flagellum-dependent cell motility →	-0.072	-1.422	.003	.003	2	11
LUNG_NSCLC_LUAD	Regulation of protein localization to nucleus →	+0.060	+1.664	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of protein-containing complex assembly →	+0.086	+1.673	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,904 associations by consensus.

Positive regulation of autophagy by ATG9B expression — UPPER_AERODIGESTIVE_TRACT

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