ATG9A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATG9A mutation is significantly associated with the RNA expression of many other genes, with 3,963 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATG9A-associated genes across cancer lineages are CDCA2, SFXN1, and VPS53. Each is linked with ATG9A in more than 2 cancer types. Because this analysis shows association rather than direction, both ATG9A-to-partner and partner-to-ATG9A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG9A→partner) and Y-score (partner→ATG9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCDCA2 →+0.786+2.115<.001<.00133
UCECSFXN1 →+0.476+2.523<.001<.00133
UCECVPS53 →+0.361+2.753<.001<.00133
BRCARNA5SP271 →+0.573+5.148<.001.00832
CESCRN7SL813P →+0.211+6.103<.001<.00132
CESCLINC02706 →+0.048+4.984.002.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,963 associations by consensus.

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