Across TCGA patient cohorts, ATG9A mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATG9A-associated genes across cancer lineages are ATM, 4E-BP1_pT37_T46, and Caspase-7-cleavedD198. Each is linked with ATG9A in more than 3 cancer types. Because this analysis shows association rather than direction, both ATG9A-to-partner and partner-to-ATG9A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG9A→partner) and Y-score (partner→ATG9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.481	-2.571	.001	.010	3	4
UCEC	4E-BP1_pT37_T46 →	-0.342	-1.584	.006	.009	3	4
UCEC	Caspase-7-cleavedD198 →	+0.790	+1.867	<.001	.004	3	3
UCEC	EGFR_pY1068 →	-0.220	-1.584	.008	.009	3	2
UCEC	eIF4E →	+0.187	+3.472	.008	.002	3	2
UCEC	MEK1 →	+0.432	+2.736	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

ATG9A survival (RNA) · tumor vs normal (RNA) · all ATG9A data types