Across TCGA cell cohorts, ATG9A mutation is significantly associated with the RNA expression of many other genes, with 306 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATG9A-associated genes across cancer lineages are LRIT1, GML, and OR1L3. Each is linked with ATG9A in more than 1 cancer types. Because this analysis shows association rather than direction, both ATG9A-to-partner and partner-to-ATG9A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG9A→partner) and Y-score (partner→ATG9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	LRIT1 →	+0.163	+5.169	<.001	.004	3	2
BLOOD_Leukemia	GML →	+0.078	+4.152	<.001	.009	3	2
BLOOD_Leukemia	OR1L3 →	+0.085	+4.276	<.001	.007	3	2
BONE	IL25 →	+0.066	+5.169	<.001	.004	3	1
BONE	OR1L6 →	+0.020	+5.169	<.001	.004	3	1
BONE	C2orf80 →	+0.126	+5.169	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 306 associations by consensus.

Exploration

ATG9A survival (RNA) · tumor vs normal (RNA) · all ATG9A data types