ATG5

Across TCGA patient cohorts, ATG5 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,041 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATG5-associated proteins across cancer lineages are SYNCRIP, VTA1, and ATG16L1. Each is linked with ATG5 in more than 5 cancer types. Because this analysis shows association rather than direction, both ATG5-to-partner and partner-to-ATG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATG5 versus SYNCRIP in BRCA, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG5→partner) and Y-score (partner→ATG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SYNCRIP →	+0.335	+0.408	.001	.008	3	6
BRCA	VTA1 →	+0.445	+0.683	<.001	<.001	3	6
BRCA	ATG16L1 →	+0.250	+0.551	.001	<.001	3	5
LSCC	ARID1B →	+0.290	+0.427	<.001	<.001	3	5
GBM	QRSL1 →	+0.351	+0.436	<.001	<.001	3	5
LSCC	PPIL4 →	+0.289	+0.588	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,041 associations by consensus.

ATG5 vs SYNCRIP — BRCA

Explore this scatter interactively →