ATG5

Across TCGA patient cohorts, ATG5 protein abundance is significantly associated with the RNA expression of many other genes, with 16,436 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATG5-associated genes across cancer lineages are KAT2A, CD164, and UFL1. Each is linked with ATG5 in more than 4 cancer types. Because this analysis shows association rather than direction, both ATG5-to-partner and partner-to-ATG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATG5 versus KAT2A in LSCC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG5→partner) and Y-score (partner→ATG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KAT2A →	-0.709	-0.177	<.001	<.001	3	5
BRCA	CD164 →	+0.698	+0.238	<.001	<.001	3	5
BRCA	UFL1 →	+0.506	+0.192	<.001	<.001	3	5
BRCA	QTRT1 →	-0.581	-0.228	.001	<.001	3	5
UCEC	HROB →	-0.661	-0.185	.005	.005	3	5
BRCA	MTBP →	-0.669	-0.240	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,436 associations by consensus.

ATG5 vs KAT2A — LSCC

Explore this scatter interactively →