ATG4C

Across TCGA patient cohorts, ATG4C protein abundance is significantly associated with the RNA expression of many other genes, with 11,483 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATG4C-associated genes across cancer lineages are CTSH, CD3G, and CD74. Each is linked with ATG4C in more than 4 cancer types. Because this analysis shows association rather than direction, both ATG4C-to-partner and partner-to-ATG4C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATG4C versus CTSH in LUAD, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG4C→partner) and Y-score (partner→ATG4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CTSH →	+1.093	+0.179	<.001	.004	3	5
LSCC	CD3G →	+0.690	+0.203	<.001	<.001	3	5
COAD	CD74 →	+1.182	+0.558	.001	.004	3	5
LUAD	TEDC2 →	-0.633	-0.157	<.001	.002	3	4
LUAD	KPNA2 →	-0.760	-0.173	<.001	.002	3	4
UCEC	CBX7 →	+0.553	+0.195	.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,483 associations by consensus.

ATG4C vs CTSH — LUAD

Explore this scatter interactively →