ATG4B

Across TCGA patient cohorts, ATG4B RNA expression is significantly associated with the protein abundance of many other proteins, with 8,455 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATG4B-associated proteins across cancer lineages are SF3B3, AQR, and ILKAP. Each is linked with ATG4B in more than 4 cancer types. Because this analysis shows association rather than direction, both ATG4B-to-partner and partner-to-ATG4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATG4B versus SF3B3 in LSCC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG4B→partner) and Y-score (partner→ATG4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SF3B3 →	+0.160	+0.323	.001	<.001	3	5
GBM	AQR →	+0.251	+0.268	<.001	<.001	3	4
GBM	ILKAP →	+0.245	+0.195	<.001	<.001	3	4
GBM	GTF2I →	+0.428	+0.292	<.001	<.001	3	4
LUAD	HNRNPA3 →	+0.205	+0.339	<.001	.001	3	4
LUAD	ALG5 →	-0.347	-0.342	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,455 associations by consensus.

ATG4B vs SF3B3 — LSCC

Explore this scatter interactively →