ATG4B

Across TCGA patient cohorts, ATG4B protein abundance is significantly associated with the RNA expression of many other genes, with 8,100 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ATG4B-associated genes across cancer lineages are DTYMK, CAPN11, and PSMD1. Each is linked with ATG4B in more than 5 cancer types. Because this analysis shows association rather than direction, both ATG4B-to-partner and partner-to-ATG4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATG4B versus DTYMK in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG4B→partner) and Y-score (partner→ATG4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DTYMK →	+0.876	+0.290	<.001	<.001	3	6
CCRCC	CAPN11 →	-0.455	-0.158	.003	.003	3	4
UCEC	PSMD1 →	+0.320	+0.208	<.001	<.001	3	4
UCEC	STK25 →	+0.753	+0.213	<.001	<.001	3	4
OV	NDUFA10 →	+0.463	+0.367	<.001	<.001	3	4
HNSC	CNOT9 →	+0.484	+0.299	<.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,100 associations by consensus.

ATG4B vs DTYMK — UCEC

Explore this scatter interactively →