ATG4AP1

Across TCGA patient cohorts, ATG4AP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,700 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ATG4AP1-associated GO terms across cancer lineages are Nucleoside phosphate biosynthetic process, Regulation of generation of precursor metabolites and energy, and Ribose phosphate biosynthetic process. Each is linked with ATG4AP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ATG4AP1-to-partner and partner-to-ATG4AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside phosphate biosynthetic process grouped by ATG4AP1-low versus ATG4AP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG4AP1→partner) and Y-score (partner→ATG4AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nucleoside phosphate biosynthetic process →	+0.061	+0.041	<.001	<.001	3	7
STAD	Regulation of generation of precursor metabolites and energy →	+0.057	+0.041	<.001	<.001	3	7
STAD	Ribose phosphate biosynthetic process →	+0.067	+0.043	<.001	<.001	3	7
STAD	Regulation of carbohydrate metabolic process →	+0.048	+0.045	<.001	<.001	3	7
UCEC	Negative regulation of peptidyl-serine phosphorylation →	+0.050	+0.027	<.001	<.001	3	7
STAD	Protein K48-linked deubiquitination →	+0.056	+0.050	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,700 associations by consensus.

Nucleoside phosphate biosynthetic process by ATG4AP1 expression — STAD

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