ATG4AP1

Across TCGA pan-cancer cohorts, ATG4AP1 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated ATG4AP1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ATG4AP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATG4AP1 expression acts as an unfavorable survival marker, although some lineages such as GBM and UCEC show a favorable association.

ACC, LUSC, and CESC are the cancer types where ATG4AP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.010	0.624	<.001	105	view →
LUSC	DFS	Tertile	All	0.464	0.809	<.001	81	view →
CESC	DFS	Tertile	III,IV	0.199	0.737	.001	72	view →
THYM	DFS	Tertile	All	0.091	0.884	<.001	36	view →
KIRC	DFS	Tertile	IV	0.266	0.651	<.001	36	view →
LGG	OS	Tertile	All	0.366	0.803	.005	24	view →
LUAD	DFS	Tertile	III,IV	0.235	0.649	.017	21	view →
READ	OS	Tertile	III,IV	0.644	0.932	<.001	15	view →
STAD	OS	Quartile	IV	0.156	0.484	.005	12	view →
GBM	OS	Tertile	All	0.409	0.238	.033	6	view →
UCEC	DFS	Tertile	II,III,IV	0.955	0.810	.047	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

ATG4AP1–ACC (DFS)

Open the ACC breakdown →