ATG2B

Across TCGA cell cohorts, ATG2B mutation is significantly associated with the RNA expression of many other genes, with 478 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATG2B-associated genes across cancer lineages are GUCA2A, C16orf90, and C14orf180. Each is linked with ATG2B in more than 1 cancer types. Because this analysis shows association rather than direction, both ATG2B-to-partner and partner-to-ATG2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GUCA2A grouped by ATG2B-low versus ATG2B-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG2B→partner) and Y-score (partner→ATG2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GUCA2A →	+0.486	+3.584	.008	.008	3	2
URINARY_TRACT	C16orf90 →	+0.023	+5.087	<.001	.004	3	2
LARGE_INTESTINE	C14orf180 →	+0.089	+2.155	<.001	.005	3	2
BLOOD_Leukemia	CSN1S1 →	+0.181	+2.133	.001	.008	3	2
BLOOD_Leukemia	UBE2M →	+0.478	+3.115	.004	.009	3	2
BLOOD_Leukemia	NEK5 →	+0.384	+3.257	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 478 associations by consensus.

GUCA2A by ATG2B expression — OESOPHAGUS

Explore this box plot interactively →