ATG14

Across TCGA patient cohorts, ATG14 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,897 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ATG14-associated proteins across cancer lineages are PPP2R5E, GMFB, and MTHFD1. Each is linked with ATG14 in more than 7 cancer types. Because this analysis shows association rather than direction, both ATG14-to-partner and partner-to-ATG14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATG14 versus PPP2R5E in PDAC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG14→partner) and Y-score (partner→ATG14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PPP2R5E →	+0.339	+0.302	<.001	<.001	3	8
PDAC	GMFB →	+0.593	+0.290	<.001	<.001	3	8
GBM	MTHFD1 →	+0.295	+0.373	<.001	<.001	3	7
CCRCC	CDC42BPB →	+0.232	+0.434	<.001	<.001	3	7
GBM	MTA1 →	+0.358	+0.272	<.001	<.001	3	6
LSCC	TRMT5 →	+0.356	+0.401	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,897 associations by consensus.

ATG14 vs PPP2R5E — PDAC

Explore this scatter interactively →