ATG10

Across TCGA patient cohorts, ATG10 mutation is significantly associated with the RNA expression of many other genes, with 749 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATG10-associated genes across cancer lineages are RNU5E-9P, NUDT4P2, and RNA5SP411. Each is linked with ATG10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATG10-to-partner and partner-to-ATG10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5E-9P grouped by ATG10-low versus ATG10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG10→partner) and Y-score (partner→ATG10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU5E-9P →	+0.272	+4.148	<.001	.006	3	2
UCEC	NUDT4P2 →	+0.053	+3.484	<.001	.001	3	2
UCEC	RNA5SP411 →	+2.080	+2.879	<.001	<.001	3	2
LUAD	DEFB103A →	+0.109	+7.930	<.001	.008	3	1
LUAD	RNU6-1047P →	+0.412	+7.930	<.001	.008	3	1
LUAD	OFD1P9Y →	+0.039	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 749 associations by consensus.

RNU5E-9P by ATG10 expression — UCEC

Explore this box plot interactively →