ATG10

Across TCGA pan-cancer cohorts, ATG10 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ATG10 data layer compared with 2 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher ATG10 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATG10 expression acts as an unfavorable survival marker, although some lineages such as READ and KIRC show a favorable association.

KICH, READ, and KIRC are the cancer types where ATG10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.556	0.968	<.001	99	view →
READ	DFS	Quartile	All	0.965	0.647	<.001	89	view →
KIRC	OS	Tertile	All	0.714	0.528	<.001	83	view →
LUAD	OS	Quartile	All	0.634	0.766	.003	64	view →
LIHC	OS	Median	All	0.615	0.759	<.001	57	view →
LGG	OS	Median	All	0.749	0.871	<.001	29	view →
SKCM	DFS	Quartile	All	0.699	0.482	<.001	25	view →
KIRP	DFS	Quartile	II,III,IV	0.940	0.230	.012	24	view →
STAD	DFS	Quartile	IV	0.119	0.551	.007	21	view →
UVM	OS	Median	All	0.392	0.890	<.001	19	view →
ESCA	OS	Tertile	IV	0.856	0.219	.024	12	view →
SCLC	DFS	Median	All	0.841	0.331	.006	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ATG10–KICH (DFS)

Open the KICH breakdown →