ATG10

Across TCGA patient cohorts, ATG10 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATG10-associated genes across cancer lineages are Myosin-IIa and MEK1. Each is linked with ATG10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATG10-to-partner and partner-to-ATG10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myosin-IIa grouped by ATG10-low versus ATG10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG10→partner) and Y-score (partner→ATG10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Myosin-IIa →	-0.283	-2.992	.008	.036	3	1
UCEC	MEK1 →	+0.518	+3.169	.009	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Myosin-IIa by ATG10 expression — UCEC

Explore this box plot interactively →