ATG10

Across TCGA cell cohorts, ATG10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,882 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATG10-associated GO terms across cancer lineages are Mismatch repair, Centriole-centriole cohesion, and Dihydrofolate metabolic process. Each is linked with ATG10 in more than 11 cancer types. Because this analysis shows association rather than direction, both ATG10-to-partner and partner-to-ATG10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mismatch repair grouped by ATG10-low versus ATG10-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG10→partner) and Y-score (partner→ATG10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mismatch repair →	+0.085	+0.700	.002	<.001	3	12
OVARY	Centriole-centriole cohesion →	+0.087	+0.524	<.001	.008	3	11
OESOPHAGUS	Dihydrofolate metabolic process →	+0.130	+0.536	.002	.009	2	12
LUNG_NSCLC_LUSC	Protein localization to site of double-strand break →	+0.082	+0.657	.002	.008	3	10
BLOOD_Myeloma	Regulation of chromosome organization →	+0.061	+0.680	.003	.003	3	10
BLOOD_Myeloma	Error-prone translesion synthesis →	+0.100	+0.717	.006	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,882 associations by consensus.

Mismatch repair by ATG10 expression — BONE

Explore this box plot interactively →