ATF7IP2

Across TCGA patient cohorts, ATF7IP2 mutation is significantly associated with the RNA expression of many other genes, with 2,169 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATF7IP2-associated genes across cancer lineages are TRAJ21, VDAC1P11, and MIR1296. Each is linked with ATF7IP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATF7IP2-to-partner and partner-to-ATF7IP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ21 grouped by ATF7IP2-low versus ATF7IP2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF7IP2→partner) and Y-score (partner→ATF7IP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TRAJ21 →	+0.446	+3.345	<.001	.008	3	2
SKCM	VDAC1P11 →	+0.088	+2.257	<.001	.003	3	2
COAD	MIR1296 →	+0.754	+4.792	.002	.003	3	2
COAD	PSMA6P3 →	+0.272	+4.893	<.001	.005	3	2
COAD	LINC02697 →	+0.190	+4.754	<.001	.003	3	2
UCEC	ZNF221 →	+0.328	+2.021	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,169 associations by consensus.

TRAJ21 by ATF7IP2 expression — CESC

Explore this box plot interactively →