ATF7IP2

Across TCGA pan-cancer cohorts, ATF7IP2 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ATF7IP2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ATF7IP2 RNA is repressed in tumor relative to normal tissue. In most cancer types ATF7IP2 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and STAD are the cancer types where ATF7IP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATF7IP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	III,IV	−1.745	<.001	11	view →
THCA	Male	III,IV	−1.347	<.001	10	view →
STAD	Female	All	+1.415	<.001	8	view →
COAD	All	All	+0.588	<.001	6	view →
KIRC	Male	II,III,IV	−0.405	<.001	6	view →
KIRP	All	All	−0.460	.001	5	view →
BRCA	Female	II,III,IV	+0.490	<.001	4	view →
PRAD	All	All	−0.426	.001	2	view →
CHOL	Female	All	−0.980	.010	1	view →
LIHC	Male	All	+0.402	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

ATF7IP2–KICH

Open the KICH breakdown →