ATF7IP2

Across TCGA cell cohorts, ATF7IP2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATF7IP2-associated genes across cancer lineages are DCD, RBMY1E, and COX6A2. Each is linked with ATF7IP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATF7IP2-to-partner and partner-to-ATF7IP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCD grouped by ATF7IP2-low versus ATF7IP2-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF7IP2→partner) and Y-score (partner→ATF7IP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	DCD →	+0.046	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	RBMY1E →	+0.820	+4.643	.002	.008	3	1
LARGE_INTESTINE	COX6A2 →	+0.068	+4.022	<.001	.006	3	1
LARGE_INTESTINE	DEFA4 →	+0.026	+4.022	<.001	.006	3	1
LARGE_INTESTINE	BPIFB6 →	+0.016	+4.022	<.001	.006	3	1
LARGE_INTESTINE	TSPY2 →	+0.039	+3.632	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

DCD by ATF7IP2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →