ATF7IP

Across TCGA pan-cancer cohorts, ATF7IP mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ATF7IP data layer compared with 25 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ATF7IP mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ATF7IP expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

LSCC, LUAD, and PDAC are the cancer types where ATF7IP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	1.000	0.924	.004	13	view →
LUAD	OS	Median	III,IV	0.756	0.233	.005	8	view →
PDAC	DFS	Median	II,III,IV	0.481	0.251	.004	5	view →
GBM	DFS	Tertile	All	0.384	0.231	.025	3	view →
UCEC	OS	Quartile	All	0.919	1.000	.047	2	view →
HNSC	OS	Quartile	All	0.819	0.911	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ATF7IP–LSCC (DFS)

Open the LSCC breakdown →