ATF7IP

Across TCGA patient cohorts, ATF7IP mutation is significantly associated with the RNA expression of many other genes, with 3,699 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATF7IP-associated genes across cancer lineages are TXN2P1, ZFPL1, and GOLGA2. Each is linked with ATF7IP in more than 3 cancer types. Because this analysis shows association rather than direction, both ATF7IP-to-partner and partner-to-ATF7IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TXN2P1 grouped by ATF7IP-low versus ATF7IP-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF7IP→partner) and Y-score (partner→ATF7IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TXN2P1 →	+0.639	+3.656	<.001	.005	3	4
UCEC	ZFPL1 →	+0.330	+1.801	.002	.001	3	4
LUAD	GOLGA2 →	+0.557	+3.369	.001	.004	3	4
CESC	MIR7974 →	+0.670	+4.270	<.001	<.001	3	4
UCEC	UBN1 →	+0.418	+1.850	<.001	<.001	3	4
UCEC	CIZ1 →	+0.381	+1.981	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,699 associations by consensus.

TXN2P1 by ATF7IP expression — COAD

Explore this box plot interactively →