ATF7

Across TCGA patient cohorts, ATF7 mutation is significantly associated with the RNA expression of many other genes, with 3,366 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATF7-associated genes across cancer lineages are RPS29P32, RNU6-750P, and MTND1P6. Each is linked with ATF7 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATF7-to-partner and partner-to-ATF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P32 grouped by ATF7-low versus ATF7-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF7→partner) and Y-score (partner→ATF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RPS29P32 →	+0.683	+4.591	<.001	.004	3	3
LUSC	RNU6-750P →	+0.598	+4.781	<.001	.003	3	2
HNSC	MTND1P6 →	+0.046	+5.655	<.001	.004	3	2
LUAD	FAM25BP →	+0.467	+5.410	<.001	.005	3	2
HNSC	OR52N5 →	+0.050	+5.736	<.001	.003	3	1
HNSC	SNORD3P1 →	+0.184	+5.182	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,366 associations by consensus.

RPS29P32 by ATF7 expression — LUSC

Explore this box plot interactively →