Across TCGA cell cohorts, ATF6B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,717 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ATF6B-associated GO terms across cancer lineages are snoRNA guided rRNA pseudouridine synthesis, Cilium or flagellum-dependent cell motility, and Regulation of ATF6-mediated unfolded protein response. Each is linked with ATF6B in more than 13 cancer types. Because this analysis shows association rather than direction, both ATF6B-to-partner and partner-to-ATF6B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF6B→partner) and Y-score (partner→ATF6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	snoRNA guided rRNA pseudouridine synthesis →	-0.098	-1.155	.004	.004	3	14
BONE	Cilium or flagellum-dependent cell motility →	-0.103	-0.723	.001	.003	3	13
LARGE_INTESTINE	Regulation of ATF6-mediated unfolded protein response →	+0.190	+0.966	<.001	<.001	3	13
BONE	Cilium-dependent cell motility →	-0.103	-0.723	.001	.003	3	13
STOMACH	Endosomal transport →	+0.057	+0.517	.004	.005	2	13
UPPER_AERODIGESTIVE_TRACT	Membrane protein ectodomain proteolysis →	+0.164	+1.090	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,717 associations by consensus.

Exploration

ATF6B survival (RNA) · tumor vs normal (RNA) · all ATF6B data types