ATF6

Across TCGA patient cohorts, ATF6 protein abundance is significantly associated with the RNA expression of many other genes, with 4,313 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ATF6-associated genes across cancer lineages are NMRK1, MPP2, and PLA1A. Each is linked with ATF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATF6-to-partner and partner-to-ATF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATF6 versus NMRK1 in OV, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF6→partner) and Y-score (partner→ATF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NMRK1 →	-0.460	-0.302	.007	.007	3	2
OV	MPP2 →	+1.038	+0.400	<.001	.002	3	2
OV	PLA1A →	-0.954	-0.525	.002	.001	3	2
OV	ADH5 →	-0.907	-0.376	.003	<.001	3	2
OV	TDRD3 →	-0.540	-0.459	.007	.009	3	2
LUAD	PSMB5 →	+0.374	+0.295	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,313 associations by consensus.

ATF6 vs NMRK1 — OV

Explore this scatter interactively →