ATF3

Across TCGA patient cohorts, ATF3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,872 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ATF3-associated genes across cancer lineages are AQP9, VGLL1, and FFAR2. Each is linked with ATF3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ATF3-to-partner and partner-to-ATF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATF3 versus AQP9 in HNSC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF3→partner) and Y-score (partner→ATF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	AQP9 →	+1.840	+1.966	.001	<.001	3	4
BRCA	VGLL1 →	+1.893	+0.594	.002	.007	3	3
HNSC	FFAR2 →	+2.111	+2.479	<.001	<.001	3	3
GBM	APOBEC3A →	+1.130	+1.178	.001	.001	3	3
HNSC	FCGR3B →	+2.443	+2.320	<.001	.001	3	3
HNSC	CXCR1 →	+2.274	+2.271	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,872 associations by consensus.

ATF3 vs AQP9 — HNSC

Explore this scatter interactively →