ATF3

Across TCGA patient cohorts, ATF3 mutation is significantly associated with the RNA expression of many other genes, with 108 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATF3-associated genes across cancer lineages are MIR1179, GRAMD4P5, and MIR548AP. Each is linked with ATF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATF3-to-partner and partner-to-ATF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1179 grouped by ATF3-low versus ATF3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF3→partner) and Y-score (partner→ATF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR1179 →	+1.171	+7.741	<.001	.009	3	2
UCEC	GRAMD4P5 →	+0.024	+4.060	<.001	.006	3	2
BRCA	MIR548AP →	+0.322	+8.055	<.001	.007	3	1
CESC	IFNA13 →	+0.030	+5.103	<.001	.008	3	1
CESC	ANKRD49P3 →	+0.060	+5.103	<.001	.008	3	1
CESC	RNU7-175P →	+0.644	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 108 associations by consensus.

MIR1179 by ATF3 expression — COAD

Explore this box plot interactively →