Across TCGA patient cohorts, ATAD3C mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATAD3C-associated genes across cancer lineages are ATM, EGFR_pY1068, and A-Raf_pS299. Each is linked with ATAD3C in more than 1 cancer types. Because this analysis shows association rather than direction, both ATAD3C-to-partner and partner-to-ATAD3C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD3C→partner) and Y-score (partner→ATAD3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.611	-3.169	<.001	<.001	3	2
UCEC	EGFR_pY1068 →	-0.245	-2.000	.012	.010	3	1
UCEC	A-Raf_pS299 →	-0.104	-3.459	.027	.005	3	1
UCEC	FOXO3a_pS318_S321 →	-0.107	-1.797	.029	.025	3	1
UCEC	JNK2 →	+0.221	+2.331	.004	.019	3	1
UCEC	Ku80 →	+0.314	+2.515	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

ATAD3C survival (RNA) · tumor vs normal (RNA) · all ATAD3C data types