Across TCGA pan-cancer cohorts, ATAD3C RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ATAD3C data layer compared with 4 for mutation status.
The strongest signal is observed in uveal melanoma (UVM), where higher ATAD3C RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ATAD3C expression acts as an unfavorable survival marker, although some lineages such as UVM and LUAD show a favorable association.
UVM, LUAD, and LGG are the cancer types where ATAD3C RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.