Across TCGA cell cohorts, ATAD3C mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATAD3C-associated genes across cancer lineages are CD1C, TERB2, and OR4F15. Each is linked with ATAD3C in more than 1 cancer types. Because this analysis shows association rather than direction, both ATAD3C-to-partner and partner-to-ATAD3C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD3C→partner) and Y-score (partner→ATAD3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CD1C →	+0.033	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	TERB2 →	+0.017	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR4F15 →	+0.011	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	PRR23A →	+0.045	+4.371	<.001	.005	3	1
LARGE_INTESTINE	CLUAP1 →	+0.652	+3.215	.005	.009	3	1
LARGE_INTESTINE	DDX25 →	+0.123	+3.447	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

ATAD3C survival (RNA) · tumor vs normal (RNA) · all ATAD3C data types