ATAD1

Across TCGA patient cohorts, ATAD1 mutation is significantly associated with the RNA expression of many other genes, with 676 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATAD1-associated genes across cancer lineages are KRTAP20-3, YTHDF3-AS1, and MAP3K4-AS1. Each is linked with ATAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATAD1-to-partner and partner-to-ATAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP20-3 grouped by ATAD1-low versus ATAD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD1→partner) and Y-score (partner→ATAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KRTAP20-3 →	+0.067	+4.060	<.001	.006	3	2
UCEC	YTHDF3-AS1 →	+0.817	+3.053	<.001	<.001	3	1
UCEC	MAP3K4-AS1 →	+0.855	+2.708	<.001	.003	3	1
UCEC	ZNHIT3 →	+0.475	+3.021	.002	<.001	3	1
UCEC	TAF9 →	+0.507	+3.343	.002	.005	3	1
UCEC	SNORD91B →	+0.496	+2.257	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 676 associations by consensus.

KRTAP20-3 by ATAD1 expression — UCEC

Explore this box plot interactively →