ASZ1

Across TCGA cell cohorts, ASZ1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ASZ1-associated genes across cancer lineages are PAPOLB and SLC15A5. Each is linked with ASZ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASZ1-to-partner and partner-to-ASZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PAPOLB grouped by ASZ1-low versus ASZ1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASZ1→partner) and Y-score (partner→ASZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PAPOLB →	+0.068	+4.044	<.001	.009	3	1
LARGE_INTESTINE	SLC15A5 →	+0.017	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PAPOLB by ASZ1 expression — SKIN

Explore this box plot interactively →