ASXL3

Across TCGA patient cohorts, ASXL3 protein abundance is significantly associated with the RNA expression of many other genes, with 693 significant associations in total. OV shows the largest number of these associations.

The most reproducible ASXL3-associated genes across cancer lineages are OR7E31P, RANP8, and METAP2P1. Each is linked with ASXL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASXL3-to-partner and partner-to-ASXL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASXL3 versus OR7E31P in OV, with a Pearson correlation of -0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASXL3→partner) and Y-score (partner→ASXL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	OR7E31P →	-0.478	-0.563	.001	.002	3	2
OV	RANP8 →	-0.836	-0.910	.004	.001	3	2
OV	METAP2P1 →	-0.674	-0.584	.001	.001	3	2
CCRCC	FOLR3 →	+0.383	+0.656	.001	.001	3	1
CCRCC	FHL2 →	+0.710	+0.578	<.001	.006	3	1
CCRCC	SDC4 →	+0.630	+0.831	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 693 associations by consensus.

ASXL3 vs OR7E31P — OV

Explore this scatter interactively →