ASTN2

Across TCGA cell cohorts, ASTN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,783 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ASTN2-associated GO terms across cancer lineages are Transport along microtubule, Epidermis development, and Negative regulation of protein localization to mitochondrion. Each is linked with ASTN2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ASTN2-to-partner and partner-to-ASTN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport along microtubule grouped by ASTN2-low versus ASTN2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASTN2→partner) and Y-score (partner→ASTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Transport along microtubule →	+0.054	+1.121	<.001	<.001	3	9
PANCREAS	Epidermis development →	-0.134	-1.486	<.001	<.001	3	9
URINARY_TRACT	Negative regulation of protein localization to mitochondrion →	-0.234	-1.571	<.001	.002	3	8
BREAST	Cytoskeleton-dependent intracellular transport →	+0.048	+1.063	<.001	<.001	3	8
BREAST	Regulation of interleukin-1 beta production →	-0.111	-1.438	<.001	<.001	3	8
BREAST	Regulation of interleukin-1 production →	-0.148	-1.366	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,783 associations by consensus.

Transport along microtubule by ASTN2 expression — BREAST

Explore this box plot interactively →