Across TCGA pan-cancer cohorts, ASS1P5 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ASS1P5’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ASS1P5 RNA is repressed in tumor relative to normal tissue. In most cancer types ASS1P5 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and COAD are the cancer types where ASS1P5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ASS1P5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	II,III,IV	−0.176	<.001	8	view →
KIRC	Male	All	−0.088	<.001	8	view →
COAD	Female	II,III,IV	+0.237	.002	5	view →
BRCA	All	All	−0.018	.021	4	view →
CHOL	All	II,III,IV	−0.075	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: ASS1P5 RNA expression & survival · all ASS1P5 data types