ASPRV1

Across TCGA pan-cancer cohorts, ASPRV1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ASPRV1 data layer compared with 24 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ASPRV1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ASPRV1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCS, UCEC, and SARC are the cancer types where ASPRV1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	All	0.068	0.524	<.001	48	view →
UCEC	DFS	Median	All	0.947	0.626	.022	10	view →
SARC	OS	Median	All	0.174	0.730	.006	9	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ASPRV1–UCS (DFS)

Open the UCS breakdown →