ASPRV1

Across TCGA pan-cancer cohorts, ASPRV1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ASPRV1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ASPRV1 RNA is repressed in tumor relative to normal tissue. In most cancer types ASPRV1 is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KICH, LUAD, and THCA are the cancer types where ASPRV1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ASPRV1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	IV	−1.285	<.001	11	view →
LUAD	Female	III,IV	−1.144	<.001	9	view →
THCA	Male	II,III,IV	−0.692	<.001	9	view →
KIRP	All	III,IV	−0.696	<.001	8	view →
KIRC	Female	All	+0.607	<.001	8	view →
HNSC	All	All	+1.561	.001	6	view →
UCEC	All	II,III,IV	−1.243	<.001	6	view →
BRCA	All	II,III,IV	−0.681	<.001	6	view →
STAD	All	III,IV	+0.408	.002	5	view →
PRAD	All	All	−0.263	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

ASPRV1–KICH

Open the KICH breakdown →