ASPRV1

mass-spec protein — tumor vs normal
Tumor vs Normalmass-specBox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, ASPRV1 mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ASPRV1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ASPRV1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types ASPRV1 is over-expressed in tumor.

HNSC and LSCC are the cancer types where ASPRV1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ASPRV1 mass-spec protein (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCAllII,III,IV+0.757<.0016view →
LSCCAllAll+0.598.0152view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

ASPRV1–HNSC

Tumor-vs-normal mass-spec protein box plot for ASPRV1 in HNSC.

Open the HNSC breakdown →

Exploration