Across TCGA patient cohorts, ASPH RNA expression is significantly associated with the protein abundance of many other proteins, with 11,947 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ASPH-associated proteins across cancer lineages are RAB2A, NCOA5, and WNT5A. Each is linked with ASPH in more than 4 cancer types. Because this analysis shows association rather than direction, both ASPH-to-partner and partner-to-ASPH results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ASPH→partner) and Y-score (partner→ASPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RAB2A →	+0.428	+0.824	.001	<.001	3	5
LSCC	NCOA5 →	-0.223	-0.651	<.001	.001	3	5
LSCC	WNT5A →	+0.927	+0.757	<.001	<.001	3	4
COAD	HMGN4 →	-0.388	-0.617	.007	.001	3	4
CCRCC	PLOD2 →	+0.793	+0.527	<.001	<.001	3	4
LSCC	G6PD →	+0.786	+0.700	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,947 associations by consensus.

Exploration

ASPH survival (RNA) · tumor vs normal (RNA) · all ASPH data types