ASPG

Across TCGA patient cohorts, ASPG RNA expression is significantly associated with the protein abundance of many other proteins, with 11,723 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ASPG-associated proteins across cancer lineages are EPB41L1, ARHGEF6_S225, and EPB41L1_S870. Each is linked with ASPG in more than 5 cancer types. Because this analysis shows association rather than direction, both ASPG-to-partner and partner-to-ASPG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASPG versus EPB41L1 in HNSC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ASPG→partner) and Y-score (partner→ASPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EPB41L1 →	+0.621	+0.904	.002	.002	3	6
LSCC	ARHGEF6_S225 →	-0.640	-0.935	<.001	<.001	3	5
LSCC	EPB41L1_S870 →	+0.737	+0.830	<.001	<.001	3	5
CCRCC	FNDC3B →	-0.341	-1.374	<.001	.001	3	5
CCRCC	PPP1R13B →	+0.414	+1.713	<.001	<.001	3	4
LSCC	SPIRE2_S371 →	+0.721	+0.907	.005	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,723 associations by consensus.

ASPG vs EPB41L1 — HNSC

Explore this scatter interactively →