ASPA

Across TCGA cell cohorts, ASPA RNA expression is significantly associated with the go_rna of many other GO terms, with 856 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ASPA-associated GO terms across cancer lineages are L-aspartate biosynthetic process, Acetate metabolic process, and Positive regulation of small molecule metabolic process. Each is linked with ASPA in more than 5 cancer types. Because this analysis shows association rather than direction, both ASPA-to-partner and partner-to-ASPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-aspartate biosynthetic process grouped by ASPA-low versus ASPA-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASPA→partner) and Y-score (partner→ASPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	L-aspartate biosynthetic process →	-0.263	-1.238	<.001	<.001	3	6
SOFT_TISSUE	Acetate metabolic process →	-0.484	-0.339	<.001	.006	3	5
KIDNEY	Positive regulation of small molecule metabolic process →	+0.051	+0.677	<.001	.007	3	5
SKIN	Negative regulation of nucleotide catabolic process →	+0.118	+0.845	<.001	.001	3	4
SKIN	Negative regulation of purine nucleotide catabolic process →	+0.118	+0.845	<.001	.001	3	4
SKIN	Endosomal vesicle fusion →	+0.076	+0.979	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 856 associations by consensus.

L-aspartate biosynthetic process by ASPA expression — SKIN

Explore this box plot interactively →