ASNSD1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ASNSD1 mutation is significantly associated with the RNA expression of many other genes, with 1,295 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASNSD1-associated genes across cancer lineages are AK6P1, TCP11X3P, and GALR3. Each is linked with ASNSD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ASNSD1-to-partner and partner-to-ASNSD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AK6P1 grouped by ASNSD1-low versus ASNSD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASNSD1→partner) and Y-score (partner→ASNSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAK6P1 →+0.249+1.856<.001.00633
COADTCP11X3P →+0.181+5.251.007<.00133
UCECGALR3 →+0.330+2.053<.001.00532
READLINC00927 →+0.011+5.039.005.00832
STADMIR4674 →+0.315+4.798<.001.00632
CESCTTTY12 →+0.060+5.812<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,295 associations by consensus.

AK6P1 by ASNSD1 expression — UCEC

Box plot of AK6P1 in ASNSD1-low vs ASNSD1-high samples in UCEC.

Explore this box plot interactively →

Exploration