ASNSD1

Across TCGA pan-cancer cohorts, ASNSD1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ASNSD1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ASNSD1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ASNSD1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, KICH, and LIHC are the cancer types where ASNSD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ASNSD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+0.467	<.001	11	view →
KICH	Female	II,III,IV	−1.661	<.001	10	view →
LIHC	Male	II,III,IV	+0.875	<.001	9	view →
COAD	All	II,III,IV	+0.590	<.001	8	view →
THCA	Female	All	−0.322	<.001	8	view →
CHOL	Male	All	+1.228	<.001	5	view →
STAD	All	II,III,IV	+0.501	.004	4	view →
READ	Male	All	+0.766	.019	3	view →
ESCA	All	All	+0.790	.007	2	view →
UCEC	All	All	−0.574	.004	2	view →
KIRP	Male	All	−0.430	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ASNSD1–HNSC

Open the HNSC breakdown →