ASMTL-AS1

Across TCGA pan-cancer cohorts, ASMTL-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of ASMTL-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ASMTL-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ASMTL-AS1 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

COAD, LIHC, and KIRC are the cancer types where ASMTL-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ASMTL-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+1.435	<.001	11	view →
LIHC	All	II,III,IV	+1.167	<.001	8	view →
KIRC	All	All	+0.393	.001	8	view →
BRCA	Female	All	−0.533	<.001	6	view →
CHOL	Female	All	+3.113	<.001	3	view →
STAD	All	II,III,IV	+0.587	.012	3	view →
READ	All	All	+0.928	.012	2	view →
PRAD	All	All	+0.364	.045	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

ASMTL-AS1–COAD

Open the COAD breakdown →