ASIC5

Across TCGA patient cohorts, ASIC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,869 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ASIC5-associated GO terms across cancer lineages are Peptidyl-lysine modification, Cellular respiration, and Cell redox homeostasis. Each is linked with ASIC5 in more than 12 cancer types. Because this analysis shows association rather than direction, both ASIC5-to-partner and partner-to-ASIC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine modification grouped by ASIC5-low versus ASIC5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASIC5→partner) and Y-score (partner→ASIC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Peptidyl-lysine modification →	+0.053	+0.111	<.001	<.001	3	13
STAD	Cellular respiration →	+0.065	+0.129	<.001	<.001	3	13
STAD	Cell redox homeostasis →	+0.085	+0.147	<.001	<.001	3	13
ESCA	Mitochondrial fusion →	+0.055	+0.129	<.001	.003	3	13
STAD	RNA methylation →	+0.052	+0.083	<.001	<.001	3	12
STAD	Regulation of proteolysis involved in protein catabolic process →	+0.057	+0.126	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,869 associations by consensus.

Peptidyl-lysine modification by ASIC5 expression — STAD

Explore this box plot interactively →