ASIC5

Across TCGA cell cohorts, ASIC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 568 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ASIC5-associated GO terms across cancer lineages are Cytoplasmic translational elongation, Positive regulation of organ growth, and Cellular response to thyroid hormone stimulus. Each is linked with ASIC5 in more than 4 cancer types. Because this analysis shows association rather than direction, both ASIC5-to-partner and partner-to-ASIC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translational elongation grouped by ASIC5-low versus ASIC5-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASIC5→partner) and Y-score (partner→ASIC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cytoplasmic translational elongation →	+0.047	+0.012	.009	.003	3	4
LIVER	Positive regulation of organ growth →	-0.099	-0.066	.007	.002	3	4
BONE	Cellular response to thyroid hormone stimulus →	+0.096	+0.020	.008	.009	3	4
LUNG_NSCLC_LUAD	Glycoside metabolic process →	+0.130	+0.034	<.001	.001	3	4
LUNG_NSCLC_LUAD	Regulation of testosterone biosynthetic process →	+0.158	+0.046	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Retinal metabolic process →	+0.119	+0.029	.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 568 associations by consensus.

Cytoplasmic translational elongation by ASIC5 expression — SOFT_TISSUE

Explore this box plot interactively →