Across TCGA cell cohorts, ASIC3 mutation is significantly associated with the RNA expression of many other genes, with 426 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ASIC3-associated genes across cancer lineages are TBC1D3, PNLIP, and TPRX1. Each is linked with ASIC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASIC3-to-partner and partner-to-ASIC3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASIC3→partner) and Y-score (partner→ASIC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TBC1D3 →	+0.779	+3.954	.003	.005	3	2
BLOOD_Myeloma	PNLIP →	+0.046	+4.807	<.001	.006	3	1
BLOOD_Myeloma	TPRX1 →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Myeloma	CT47A6 →	+0.586	+4.807	<.001	.006	3	1
BLOOD_Myeloma	CCL16 →	+0.030	+4.807	<.001	.006	3	1
PANCREAS	ZSCAN1 →	+0.039	+5.000	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 426 associations by consensus.

Exploration

ASIC3 survival (RNA) · tumor vs normal (RNA) · all ASIC3 data types