ASIC2

Across TCGA cell cohorts, ASIC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,359 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ASIC2-associated GO terms across cancer lineages are Regulation of myoblast fusion, Lipoprotein transport, and Lipoprotein localization. Each is linked with ASIC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ASIC2-to-partner and partner-to-ASIC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by ASIC2-low versus ASIC2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASIC2→partner) and Y-score (partner→ASIC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of myoblast fusion →	+0.087	+0.996	<.001	.008	2	5
BONE	Lipoprotein transport →	+0.174	+2.417	<.001	<.001	3	4
BONE	Lipoprotein localization →	+0.183	+2.768	<.001	<.001	3	4
BONE	Negative regulation of cell growth involved in contact inhibition →	-0.332	-2.377	.005	<.001	3	4
BONE	Blood coagulation, intrinsic pathway →	-0.140	-1.910	.003	.001	3	4
UPPER_AERODIGESTIVE_TRACT	Response to topologically incorrect protein →	+0.050	+0.054	.009	.009	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,359 associations by consensus.

Regulation of myoblast fusion by ASIC2 expression — LUNG_SCLC

Explore this box plot interactively →